Synthesis of calcium hydroxyapatite and its use for obtaining biologically soluble matrices based on polymer fibers
DOI:
https://doi.org/10.18321/cpc363Keywords:
Calcium hydroxyapatite, eggshell, electrospinning, polymer fibers.Abstract
In this paper, we consider the possibility of synthesizing calcium hydroxyapatite (HAP) using biogenic sources of calcium carbonate, namely calcite in the shell of a chicken egg. HAP powders were synthesized by precipitation from an aqueous solution. This synthesis method allowed us to obtain HAP powders with a purity of 95%. During experimental work, it was found that the ultrasonic treatment time provides particles with more uniformity than long-term heat treatment. The synthesized HAP powder was used to obtain biologically soluble films based on polymer fibers. Films were obtained by the method of electroforming. A drug, in particular amoxicillin, was added to the solution of films at different concentrations. Experimental work showed that the thickness of the films depends on the concentration of the drug substance. Scanning electron microscopy (SEM) and X-ray diffraction (XRD) were used to characterize HAP and films.
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